By Kevin R. Loughlin
Through offering either the doctor's and patient's view, this ebook promises authoritative, useful solutions in your questions about treatment plans.
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Extra resources for 100 Questions & Answers About Prostate Disease
These conditions are considered absolute because if left untreated they can cause harm to the patient. The relative indications refer to symptoms that may or may not be bothersome to an individual patient. These include urinary frequency, nocturia (getting up at night to urinate), and decreased urinary stream. qxd 7/25/06 2:17 PM Page 27 equally. For instance, getting up three times per night may bother one man a great deal and another not at all. Therefore, whether to treat these relative symptoms depends in large measure by how much they bother the individual patients.
Qxd 7/25/06 2:17 PM Page 28 100 QUESTIONS & ANSWERS ABOUT PROSTATE DISEASE to think of this is that the prostate squeezes around the urethra and tightens its grip, resulting in increased urethral resistance to urine flow from the bladder. This increased prostatic tone, therefore, can result in the symptoms of prostatic obstruction. 29. How are alpha blockers used to treat BPH symptoms? Alpha blockers a class of drug used to treat prostate symptoms. Because norepinephrine is the signal that acts on the alpha receptors to cause smooth muscle to contract, if you block part of that signal, you should decrease the muscle contraction.
PSA is a valuable blood test that screens for prostate cancer, as discussed in Questions 5 to 11. However, 5 alpha reductase inhibitor drugs do affect PSA levels. As mentioned in Question 33, 5 alpha reductase inhibitor drugs block the conversion of testosterone to DHT, which results in shrinkage of the prostate or a decrease in prostate volume. Because prostate cells make PSA, it is reasonable to assume that as the prostate gets smaller, the PSA level will decline. qxd 7/25/06 2:17 PM Page 36 100 QUESTIONS & ANSWERS ABOUT PROSTATE DISEASE volume decrease to occur, and thus, the PSA decline is gradual.
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